Sulpiride is belong to benzamides compound as atypical antipsychotics. Hypothalamus, pons and medulla oblongata, can antagonize the D1, D2 receptors, to D3, D4 receptors also have a certain antagonism. Activate emotional effect. Its anti-stupor, withdrawal, hallucinations, paranoia and insanity is stronger, and have some antidepressant effect. There is a strong central antiemetic effect. Anticholinergic effec-t is weak, non-sedative and hypnotic effects and anti-agitation effect. . Plasma half-life of 8-9 hours, mainly excreted by the kidneys. It can be discharged from breast milk. Animal experiments are shown the product can enter the umbilical cord blood circulating through the placental barrier.
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