Amisulpride is an aniline substitute antipsychotic, optionally with the limbic system D2, D3 dopamine receptors. This product does not serotonin receptors or other histamine, cholinergic receptors, adrenergic receptor binding. Animal experiments, compared with the striatum, high-dose amisulpride main block dopamine in the middle of the limbic system neurons. Such affinity may be amisulpride spirit Inhibitory effect of extrapyramidal its reasons.
Toxicological properties of amisulpride mainly with pharmacological effects related to this compound. No toxicity associated with repeated administration of target organs was found. This compound was not teratogenic and mutagenic. Animal carcinogenicity studies show: can produce hormone-dependent tumors in rodents. But no clinical relevance in humans.
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