Medical Function of Triptorelin Acetate

Triptorelin Acetate, the active ingredient is a synthetic analogue of gonadotropin-releasing hormone, which is to improve the structure of the natural molecular structure of the sixth L-glycine was replaced by D-tryptophan to promote more efficient role and the plasma half-life is significantly longer. After injection of Decapeptyl, initially stimulate the pituitary gland to release luteinizing hormone and follicle-stimulating hormone. When the pituitary over a long period of stimulation into the refractory period, the release of gonadotropin will be reduced. When transient increase, continuous administration of triptorelin acetate results in downregulation of LH and FSH levels followed by a suppression of ovarian.

The administration of triptorelin stimulates the release of pituitary gonadotropins and leads to a transient increase in testosterone levels. While Prolonged leads to a suppression of gonadotropins and a fall in plasma testosterone to castrate levels after approximately 20 days. This is maintained for as long as the drug is administered.

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