Ranitidine hydrochloride is a hindered amine woven H2- receptor antagonists, can inhibit gastric acid secretion and gastric acid stimulation basis, can reduce gastric acid, pepsin activity is reduced but also fast-acting and long-term characteristics. It can be used for peptic ulcer, reflux esophagitis, Zollinger - Ellison syndrome and upper gastrointestinal bleeding.
Drug Interactions
1.With hepatic metabolism of warfarin, lidocaine, diazepam, propranolol and other use, the plasma concentration of ranitidine does not rise and the emergence toxicity.
2. With anticoagulants, when combined with the antiepileptic drugs than cimetidine safe.
3. With procainamide and use, procainamide can reduce clearance
4. It reduces the hepatic blood flow, and thus propranolol, lidocaine metabolism of hepatic blood flow by the large impact of the drug combination, can delay the effects of these drugs.
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