Pharmacological Action of Aminocaproic Acid

Aminocaproic Acid, a derivative and analogue of the amino acid lysine,which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis. For this reason it is effective in treatment of certain bleeding disorders, and it is marketed as Amicar.

Pharmaceutical Functions:

1. For biochemical reagents

2. for organic synthesis. As anti-plasmin fiber prion agent. Used as a hemostatic.

3. For some severe bleeding due to increased fibrinolytic activity caused significant effect. Suitable for topical bleeding or bleeding more during surgery.

4. Also used hemoptysis, gastrointestinal bleeding and other bleeding disorders and obstetrics and gynecology.

5. works by inhibiting the fibrinolytic system. Visceral surgery bleeding bleeding after plasmin is mainly used due to increased activity, such as bleeding obstetrics and gynecology, prostate, liver, pancreas and lung. Early medication or surgery preoperative medication can reduce bleeding during surgery and to reduce the amount of blood transfusion.

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